Navegação Periódicos - Artigos por assunto "radiation dose units"

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  • IPEN-DOC 17278

    COELHO, TALITA S.; FERNANDES, MARCO A.R.; YORIYAZ, HELIO ; LOUZADA, MARIO J.Q.. Analise dosimétrica de perfis de distribuições radiais de doses relativas de um aplicador de betaterapia de sup(90)Sr+sup(90)Y utilizando o código MCNP-4C e filmes radiocrônicos. Revista Brasileira de Fisica Medica, v. 4, n. 3, p. 7-10, 2011.

    Palavras-Chave: beta dosimetry; dose equivalents; dosimetry; films; m codes; measuring methods; radiation detection; radiation dose distributions; radiation dose units; radiation doses; radiation monitoring; radiation protection; radiations; strontium; strontium 90; yttrium; yttrium 90

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  • IPEN-DOC 24420

    KUAHARA, L.T. ; CORREA, E.L. ; POTIENS, M.P.A. . Análise da variação da atividade de uma amostra de 99mTc após diluição com soro fisiológico. Brazilian Journal of Radiation Sciences, v. 05, n. 03-A, p. 01-10, 2017.

    Abstract: O ativímetro é um equipamento essencial em um serviço de medicina nuclear. Garantir seu bom funcionamento e conhecer os fatores que podem influenciar na sua leitura é fundamental para que a atividade administrada ao paciente esteja correta. Vários fatores podem causar alterações na resposta do ativímetro, como o tipo de recipi- ente, geometria e volume do radioisótopo. O objetivo deste trabalho foi analisar as variações nas medições de 0,5 mL e 1,0 mL de 99mTc puro e diluído em até 2,5 mL de soro fisiológico, em recipientes utilizados em medicina nuclear. Foram encontradas variações de até 4 % nos valores medidos.

    Palavras-Chave: activity meters; metering; nuclear medicine; quality control; radiation dose units; radiation protection; technetium 99; variations; variations

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  • IPEN-DOC 27886

    ALBANO, A.M.S. ; ARTHUR, V. . Application of gamma radiation in pea (Pisum sativum L.) in nature to inhibit sprouting and increase shelf life. Brazilian Journal of Radiation Sciences, v. 9, n. 1A, p. 1-20, 2021. DOI: 10.15392/bjrs.v9i1A.1439

    Abstract: The irradiation of fresh post-harvest foods has as main interests: inhibit sprouting, increase shelf life, reduce or delay damage caused by insects and diseases. This work is a preliminary study on the use of gamma radiation in fresh peas grains (Pisum sativum L.) in order to evaluate its effects on the inhibition of sprout and its increase in shelf life. The peas were submitted at irradiation process with four radiation doses: 0 (control), 0.15, 0.30 and 0.45 kGy, in a 60Co research irradiator, with a dose rate of 0.323 kGy/h. After irradiation the samples were stored at 8 °C, being evaluated at 1, 7, 14 and 21 days by analyzes of: visual aspect, weight loss, color, hardness, pH, total soluble solids, total titratable acidity, ratio SST/TTA, water content and ash. By the results it was observed that in all parameters analyzes with gamma radiation doses used did not affect significantly in the shelf life of grains. The 0.30 kGy dose increased the germination of the peas and the 0.45 kGy dose was not sufficient to inhibit the sprouting of the peas.

    Palavras-Chave: chemical analysis; cobalt 60; food processing; gamma radiation; peas; radiation dose units; radiation effects; sprout inhibition; storage life

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  • IPEN-DOC 27822

    SARTORI, GISELLE P.; COSTA, ANDREA da; MACARINI, FERNANDO L. dos S.; MARIANO, DOUGLAS O.C.; PIMENTA, DANIEL C.; SPENCER, PATRICK J. ; NALI, LUIZ H. da S.; GALISTEO JUNIOR, ANDRES J.. Characterization and evaluation of the enzymatic activity of tetanus toxin submitted to cobalt-60 gamma radiation. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 27, p. 1-13, 2021. DOI: 10.1590/1678-9199-JVATITD-2020-0140

    Abstract: Background Tetanus toxin blocks the release of the inhibitory neurotransmitters in the central nervous system and causes tetanus and its main form of prevention is through vaccination. The vaccine is produced by inactivation of tetanus toxin with formaldehyde, which may cause side effects. An alternative way is the use of ionizing radiation for inactivation of the toxin and also to improve the potential immunogenic response and to reduce the post-vaccination side effects. Therefore, the aim of this study was to characterize the tetanus toxin structure after different doses of ionizing radiation of 60Co. Methods Irradiated and native tetanus toxin was characterized by SDS PAGE in reducing and non-reducing conditions and MALD-TOF. Enzymatic activity was measured by FRET substrate. Also, antigenic properties were assessed by ELISA and Western Blot data. Results Characterization analysis revealed gradual modification on the tetanus toxin structure according to doses increase. Also, fragmentation and possible aggregations of the protein fragments were observed in higher doses. In the analysis of peptide preservation by enzymatic digestion and mass spectrometry, there was a slight modification in the identification up to the dose of 4 kGy. At subsequent doses, peptide identification was minimal. The analysis of the enzymatic activity by fluorescence showed 35 % attenuation in the activity even at higher doses. In the antigenic evaluation, anti-tetanus toxin antibodies were detected against the irradiated toxins at the different doses, with a gradual decrease as the dose increased, but remaining at satisfactory levels. Conclusion Ionizing radiation promoted structural changes in the tetanus toxin such as fragmentation and/or aggregation and attenuation of enzymatic activity as the dose increased, but antigenic recognition of the toxin remained at good levels indicating its possible use as an immunogen. However, studies of enzymatic activity of tetanus toxin irradiated with doses above 8 kGy should be further analyzed.

    Palavras-Chave: cobalt 60; detoxification; enzyme activity; gamma radiation; irradiation; neurology; radiation dose units; tetanus; toxins; vaccines

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  • IPEN-DOC 25705

    CAMARGO, F.; GONCALVES, J.A.C. ; BUENO, C.C. . A comparison between rad-hard float zone silicon diodes as gamma dosimeter in radiation processing. Brazilian Journal of Radiation Sciences, v. 7, n. 2A, p. 1-13, 2019. DOI: 10.15392/bjrs.v7i2A.681

    Abstract: In this work, we report on the results obtained with rad-hard Standard Float Zone (STFZ) and Diffused Oxygenated Float Zone (DOFZ) silicon diodes in radiation processing dosimetry. The dosimetric probes were designed to operate in the direct current mode, as on-line radiation dosimeter. The irradiation of the samples was performed using a 60Co source with a dose rate of almost 2.4 kGy/h. The current response of each diode was measured as a function of the exposure time in steps from 5 kGy up to 50 kGy to achieve a total absorbed dose of 275 kGy. In this dose range it is observed a significant decrease in the photocurrent generated in both devices due to gamma radiation defects produced in their active volumes. To mitigate this effect, the samples were pre-irradiated with 60Co gamma rays at 700 kGy. Despite of being less sensitive, these devices presented stable and reproducible current signals with a relative sensitivity decrease of about 19% within the whole range of dose studied. The dose-response curves of the pre-irradiated diodes showed quadratic behavior with correlation coefficient higher than 0.9999 for total absorbed dose up to 275 kGy. The comparison of the diodes’ dosimetric responses evidenced that the best result was achieved with the DOFZ, which exhibited slightly higher sensitivity and stability than the STFZ devices. However, it is important to note that all pre-irradiated diodes can be used as gamma dosimeters in radiation processing applications.

    Palavras-Chave: gamma dosimetry; gamma radiation; absorbed radiation doses; comparative evaluations; zone melting; cobalt 60; silicon diodes; radiation dose units; irradiation; dose rates; oxygen; radiation dose ranges

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  • IPEN-DOC 20270

    TADDEI, M.H.T.; MACACINI, J.F.; VICENTE, R. ; MARUMO, J.T. ; TERREMOTO, L.A.A. . Determination of scaling factors to estimate the radionuclide inventory of wastes from the IEA-R1 research reactor. Journal of Radioanalytical and Nuclear Chemistry, v. 303, n. 3, p. 2467-2481, 2015.

    Palavras-Chave: iear-1 reactor; radioactive waste manangement; radioactive waste disposal; dosimetry; radiation dose distributions; radiation dose units; measuring instruments; nuclear decay; radiochemical analysis; scalers; pulse analyzers; correlation functions; cobalt 60; cesium 137

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  • IPEN-DOC 27894

    LIMA, L.M.P.R.; KODAMA, Y. ; OTUBO, L. ; SANTOS, P.S. ; VASQUEZ, P.A. . Effect of ionizing radiation on the color of botanical collections - exsiccata. Brazilian Journal of Radiation Sciences, v. 9, n. 1A, p. 1-16, 2021. DOI: 10.15392/bjrs.v9i1A.1462

    Abstract: Conservation and preservation strategies are essential to manage botanical collections specially for dried herbarium specimens also known as exsiccates, usually referring to a set of identified specimens belonging to taxa and distributed among all herbaria around the world. Particularly, these collections are very sensitive to the attack of fungi and insects. In recent years, disinfection by ionizing radiation has become an effective strategy to preserve cultural heritage objects and archived materials with excellent results. In this work, the effects on color properties of gamma radiation on exsiccates samples were studied. Thus, two exsiccates, botanical pressed and dehydrated samples were selected from the Dom Bento José Pickel Herbarium (SPSF), situated at São Paulo (Brazil). These samples comes from Asteraceae and Solanaceae families and were collected in 1946 and 1984. The irradiation was performed at the Multipurpose Gamma Irradiation Facility at IPEN applying absorbed doses of 1 kGy, 6 kGy and 10 kGy, which are values of absorbed dose for disinfestation and disinfection. Results were analyzed using colorimetry with CIELAB color space scale and scanning electron microscopy. The results showed that there were no significant changes on colorimetric morphological properties of the samples.

    Palavras-Chave: absorbed radiation doses; absorption spectroscopy; botany; cobalt 60; disinfestation; fungi; gamma radiation; morphology; pest control; radiation dose units

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  • IPEN-DOC 27874

    DELGADO VIEIRA, A.C.; KODAMA, Y. ; OTUBO, L. ; SANTOS, P.S. ; VASQUEZ SALVADOR, P.A. . Effect of ionizing radiation on the color of featherwork. Brazilian Journal of Radiation Sciences, v. 9, n. 1A, p. 1-18, 2021. DOI: 10.15392/bjrs.v9i1A.1367

    Abstract: Featherwork collections are usually stored and managed by ethnographic museums. Even though the featherwork manufacturing is still practiced by the indigenous communities, the offer of raw material and the contact with the surrounding society ended up reducing the production scale of such objects. Consequently, the preservation of the material culture is very important, particularly in museums. Biodegradation can affect featherworks mainly by xylophagous insects and moths’ action. The tropical Brazilian weather contributes to the contamination and proliferation of insects and fungi making the preservation conditions difficult. The use of gamma radiation for the disinfection of cultural heritage objects has shown to be a safe process and an excellent alternative to traditional methods usually involving toxic chemical pesticides. In this work are presented the preliminary results of the ionizing radiation effects on the color and morphological properties of a featherwork from the Museum of Archeology and Ethnology of the University of São Paulo (MAE/USP). Samples of feathers were selected from the artifact and irradiated with gamma rays at the Multipurpose Gamma Irradiation Facility at IPEN, applying absorbed doses between 0.5 kGy to 200 kGy. The results shown had no significant changes on color and morphological properties within the disinfection absorbed dose range applied.

    Palavras-Chave: calorimetry; cobalt 60; disinfestation; feathers; fungi; insects; irradiation; morphological changes; preservation; radiation dose units; radiation doses; radiation effects

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  • IPEN-DOC 27357

    SÁ, ANA P.N. de ; NEGRAO, BIANCA G. ; NABESHIMA, ELIZABETH H.; KOIKE, AMANDA C.R. ; VILLAVICENCIO, ANNA L.C.H. . Effect of ionizing radiation on traditional and bacon “farofa”. Radiation Physics and Chemistry, v. 179, p. 1-7, 2021. DOI: 10.1016/j.radphyschem.2020.109109

    Abstract: Seasoned “farofa” is a typical Brazilian dish made with toasted cassava flour. It is known that ionizing radiation is widely employed to improve food products extending its shelf life. In this context, this work analyzes the effects of ionizing radiation on the rheological and physicochemical properties of bacon (BF) and traditional (TF) “farofa”. The samples were obtained from local markets (São Paulo/Brazil) and irradiated in the electron beam accelerator of Nuclear and Energy Research Institute (IPEN/CNEN-SP, São Paulo, Brazil) in doses of 1, 5 and 10 kGy, and analyzed on the first, fifteenth and thirtieth storage day. The results showed that the irradiated TF and BF samples displayed acidic pH throughout the storage period, regardless of dose increase. The different irradiation doses did not significantly affect (Tukey test p > 0.05) the water activity, keeping the products in the safe range. The colorimetric analysis, also showed no significant difference (p ≥ 0.05) among the samples and ionizing radiation doses, indicating that the yellowish coloration remained stable throughout the experiment. After the thirtieth day, the moisture of the TF and BF samples ranged from 7.06% to 9.75%. Irradiation had a significant impact on the viscosity profile and texture characteristics of the “farofa”, such as hardness, cohesiveness, and the springiness at 5 and 10 kGy.

    Palavras-Chave: chemical properties; flour; food industry; food processing; ionizing radiations; oxidation; radiation dose units; radiation effects; radurization; technology utilization

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  • IPEN-DOC 24242

    CARVALHO, G.S.M.; FERREIRA, P.Z.; DANTAS, N.O.; SILVA, A.C.A.; PERINI, A.P.; CALDAS, L.V.E. ; CARRERA, B.N.S.; WATANABE, S.; NEVES, L.P. . Evaluation of glasses containing cadmium for high dose dosimetry by the thermoluminescence technique. Brazilian Journal of Radiation Sciences, v. 05, n. 03-A, p. 01-06, 2017. DOI: 10.15392/bjrs.v5i3.285

    Abstract: New glass matrices were evaluated for high dose dosimetry by the thermoluminescence technique. Their nominal com-position are 20Li2CO3.10Al2O3.15CdO.55B2O3 and 20Li2CO3.10Al2O3.20CdO.50B2O3 (mol%). The glass matrices were irradiated with different doses: 50, 100, 200, 500, 700 and 900 Gy, and the thermoluminescence emission curves were obtained for each of these values. The results show a great potential of using these matrices in high dose dosime-try.

    Palavras-Chave: cadmium; glass scintillators; luminescent dosemeters; quality control; radiation dose units; radiation protection; thermoluminescence

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  • IPEN-DOC 27891

    FRANCO, J.G. ; SILVA, R.M.G. da; SUGUIMOTO, R.Y.; FRANCO, S.S.H.; VILLAVICENCIO, A.L.C.H.; ARTHUR, V. . Glycine max oil physical-chemical quality obtained of irradiated seeds. Brazilian Journal of Radiation Sciences, v. 9, n. 1A, p. 1-11, 2021. DOI: 10.15392/bjrs.v9i1A.1450

    Abstract: Ionizing radiation applied to agriculture has mainly benefited food production, as it reduces natural losses caused by physiological processes, as well as eliminating or reducing microorganisms, parasites and pests. In addition, this technique also allows the production of mutants with characteristics of greater productivity, precocity, smaller size, greater resistance to diseases and pests. These mutants are used to obtain new varieties of species of agronomic interest. The objective of this study was to evaluate the physic-chemical quality of the oil extracted from seeds of G. max (soybean) obtained from irradiated seeds with different doses of gamma radiation (0, 25, 50, 75 and 100 Gy of a Cobalt-60 source, type Gammacell-220 installed in CENA-USP). The physic-chemical analyzes included: AOCS Cd-3d-63, AOCS Cd-3-25 and AOCS Cd-1-25, Acids Index (I.A.), Saponification Index (I.S.), Iodide Index (I.I.), respectively. All analytical determinations were performed at least in triplicates. The values found for I.A., for I.S. and for I.I., did not differ from the oil sample obtained from soybean seeds from control subjects (without irradiation) regardless of the concentration and dose of radiation applied to the seeds. The oil analyzed did not show physical-chemical variation in comparison with the oil obtained from non-irradiated seeds, thus suggesting the absence of modifications in these parameters after the genetic improvement induced by the radiation.

    Palavras-Chave: agriculture; cobalt 60; gamma radiation; glycine; irradiation; physical chemistry; radiation dose units; radiation doses; radiation effects; seeds; soybeans; toxicity

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  • IPEN-DOC 27213

    COSTA, NATHALIA A. ; PATALLO, ILEANA S.; DIMITRIADIS, ALEX; SARAIVA, CRYSTIAN W.C.; POTIENS, MARIA da P.A. . Phantom development and implementation for Gamma Knife® dosimetry. Radiation Physics and Chemistry, v. 167, p. 1-5, 2020. DOI: 10.1016/j.radphyschem.2019.108355

    Abstract: Stereotactic radiosurgery is a procedure that primarily treats intracranial lesions to destroy tumour cells that are inaccessible surgically. Gamma Knife® is a stereotactic radiosurgery unit that can treat brain lesions using 60Co beams, non-invasively. Fields from Gamma Knife® helmets are considered small, therefore, in order to ensure accurate dosimetry, detectors for dose measurements have to be carefully chosen. The IAEA TRS 483 code of practice is a standardized guide for dosimetric procedures and indication of detectors for reference dosimetry of small fields used in radiotherapy beams. The objective of this work was to assess the implementation of the TRS 483 recommendations for Gamma Knife® dosimetry, using two micro-ionization chambers, Exradin A16 and PTW Pinpoint 3D 31016. An acrylic phantom with the same dimensions as those provided by Elekta, Gamma Knife’s manufacturer, was built as an alternative. The phantom was characterized for its implementation for Gamma Knife® dosimetry and to be used as part of an audit kit by a Secondary Standard Dosimetry Laboratory (SSDL) in Brazil. Alanine pellets were used as reference detector. Dosimetry results for the acrylic phantom were compared with the ones obtained in phantoms specified by Elekta, which are made of Acrylonitrile Butadiene Styrene (ABS) and Solid Water materials. TRS 483 recommended correction factors were used to calculate the absorbed dose to the water taking into consideration the phantom material. Absorbed dose measurements performed using the designed acrylic phantom showed results comparable to the ones obtained with commercially available phantoms. The new phantom is suitable for Gamma Knife reference and relative dosimetry. The results of this work aim to contribute to the implementation of the TRS 483, mainly in the area of Gamma Knife dosimetry and the use of small volume ionization chambers.

    Palavras-Chave: radiant flux density; gamma radiation; radiation dose units; radiation sources; dosimetry; radiation protection; small intestine; phantoms; biological models; nuclear medicine; radiotherapy; surgery; brain

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  • IPEN-DOC 27890

    FRANCO, S.S.H.; FRANCO, J.G. ; FERRARI, L.; LEANDRO, R.S.R. ; ARTHUR, P.B. ; ARTHUR, V. . Propagation of mango seedlings of the cultivar "Tommy" by grafts irradiated. Brazilian Journal of Radiation Sciences, v. 9, n. 1A, p. 1-8, 2021. DOI: 10.15392/bjrs.v9i1A.1449

    Abstract: Due to difficulties of vegetative propagating of any pants, many tests were performed with ionizing radiation aiming the modification of the characteristics of the plants for obtaining of the improved genotypes and of smaller size. Rootstock “Espada” cultivar, were used to obtain mango seedlings of “Tommy” cultivar. The cuttings were irradiated with different gamma radiation doses: 0 (control), 2.5, 5.0, 7.5 and 10.0 Gy, a dose rate of 0.323 kGy/h, in a source of Cobalt-60 type Gammacell-220, installed in the Center for Nuclear Energy in Agriculture, CENA-USP. After irradiation, was performed the grafting type cleft graft. It was made the first evaluation of height of the plants from the budding grafting after 24 months. Data were subjected by statistic program (SAS) and the means were compared by Tukey test (p <0.05). From the results obtained can be concluded that the doses of 2.5 Gy stimulated growth of the plants and the lethal dose was 10.0 Gy because don’t have development of plants.

    Palavras-Chave: cobalt 60; gamma radiation; grafts; irradiation; lethal doses; mangoes; radiation dose units; radiation doses; seedlings

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  • IPEN-DOC 27889

    ARTHUR, P.B. ; VILLAVICENCIO, A.L.C.H. ; HARDER, M.N.C. ; MACHI, A.R. ; LEANDRO, R.S.R. ; ARTHUR, V. . Sterilizing of Alphitobius diaperinus (Panzer, 1797) (Coleoptera: Tenebrionidae) irradiated in pupa stage. Brazilian Journal of Radiation Sciences, v. 9, n. 1A, p. 1-7, 2021. DOI: 10.15392/bjrs.v9i1A.1445

    Abstract: The use of irradiation process in stored grain may be the solution for the losses caused in these products by insects, as it does not induce resistance in the insects and leaves no toxic residue, and is considered an efficient and safe method of control of insects. The aim of the experiment was to determine the sterilizing dose of ionizing radiation from cobalt-60 to Alphitobius diaperinus (Panzer, 1797) (Coleoptera: Tenebrionidae) in peanuts irradiated in pupa stage. The experiment was conducted in the laboratory of Radiobiology and Environment of the Center for Nuclear Energy in Agriculture - CENA / USP., Piracicaba, SP, Brazil. Peanuts samples infested with pupae of A. diaperinus were utilized in the experiment that consisted of 8 treatments with 5 repetitions. Each repetition consisted of 20 pupae a total of 100 individuals per treatment. Were irradiated with doses of 0 (control), 25, 50, 75, 100, 125, 150 and 175 Gy, in a source of cobalt-60, Gammacell-220 type, with a rate dose of 381Gy / h. The experiment was conducted in a controlled temperature of 25 ± 5 ° C and relative humidity of 70 ± 5%. After of irradiation process was evaluated of the number of emerged adult insects in each repetition in the treatments. The results showed that the sterilizing dose in F1 generation was 125 Gy and the pupa lethal dose 150 Gy. The dose of 150 Gy of gamma radiation can be used as phytosanitary treatment to control of immature stages of A. diaperinus infested peanuts.

    Palavras-Chave: cobalt 60; coleoptera; dose rates; gamma radiation; irradiation; lethal doses; peanuts; pupae; radiation dose units; radiation doses; sterilization

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  • IPEN-DOC 24386

    FERREIRA, P.Z.; CARVALHO, G.S.M.; DANTAS, N.O.; SILVA, A.C.A.; NEVES, L.P. ; CALDAS, L.V.E. ; CARRERA, B.N.S.; WATANABE, S.; PERINI, A.P.. Study of a new glass matrix by thermoluminescent technique for high-dose dosimetry. Brazilian Journal of Radiation Sciences, v. 05, n. 03-A, p. 01-07, 2017. DOI: 10.15392/bjrs.v5i3.279

    Abstract: The thermoluminescence technique is widely used for both personal and high-dose dosimetry. In this work, the thermo-luminescence technique was employed to study a new glass matrix, with nominal composition of 20Li2CO3.10Al2O3.30BaO.40B2O3 (mol%), irradiated with different doses in a 60Co radioactive source. The glow curves and the dose-response curve were obtained for radiation doses of 10, 50, 100, 200 and 700 Gy. The results showed that this new glass matrix has potential use in high-dose dosimetry.

    Palavras-Chave: radiation dose units; irradiation; dosimetry; cobalt 60; glass; materials

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  • IPEN-DOC 27865

    CHIERENTIN, G.S. ; TEIXEIRA, B.S. ; MASTRO, N.L. . Total phenolic compounds of irradiated chia seeds. Brazilian Journal of Radiation Sciences, v. 9, n. 1A, p. 1-9, 2021. DOI: 10.15392/bjrs.v9i1A.1331

    Abstract: Chia seeds (Salvia hispanica L.) is a good source of oil, protein, dietary fiber, minerals and polyphenolic compounds. In order to study the influence of the processing methods on the content of phenolic compounds, the objective of this work was to evaluate the effect of gamma radiation, doses 0 (control), 5, 10 and 20 kGy, on the total phenolic compounds extracted from chia seeds. Seeds were first defatted and extracts produced with proper solvents. Total phenolic content was determined according to Folin-Ciocalteu’s method and the extraction solvents applied were ethanol 100%, ethanol 70%, ethanol 50%, methanol 100%, methanol 70% and methanol 50%. When using ethanol 100%, ethanol 70 %, ethanol 50%, methanol 100% and methanol 70%, the extraction yield was independent of the absorbed dose. With methanol 50%, the irradiation process affected positively the total phenolic yield from of chia seeds. In general, the absorbed dose as well as the nature of the solvent affected the extraction yield, although in a limited manner.

    Palavras-Chave: antioxidants; cobalt 60; dose rates; food processing; gamma radiation; irradiation; radiation dose units; radiation effects; seeds

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  • IPEN-DOC 29145

    BOIANI, N.F. ; TOMINAGA, F.K. ; BORRELY, S.I. . Toxicity removal of pharmaceuticals mixtures through electron beam irradiation. Brazilian Journal of Radiation Sciences, v. 10, n. 3B, p. 1-11, 2022. DOI: 10.15392/2319-0612.2022.1838

    Abstract: Contamination of the aquatic environment by pharmaceuticals is becoming a global phenomenon of growing concern. Pharmaceuticals are partially metabolized, resulting in the excretion and release of residual into sewage, unaltered or metabolites. The wastewater treatment plants are not designed to eliminate these compounds, leading the residues into the aquatic environment. Besides, pharmaceuticals are not detected individually but as a complex mixture. Advanced oxidative processes have been applied as an alternative or complement to conventional sewage treatment processes, aiming the degradation and removal of toxic pollutants. The objective of this study was to evaluate the toxicity removal of mixtures of pharmaceuticals subjected to electron beam treatment. The aqueous solutions of each pharmaceutical were diluted in ultra-pure water and prepared in three pharmaceuticals combinations: Propranolol + Fluoxetine + Sulfadiazine; Propranolol + Fluoxetine + Diclofenac; Acetylsalicylic acid + Fluoxetine + Metformin). Electron Beam Accelerator was applied for the irradiations and the absorbed doses were 2.5-5.0 kGy. Acute toxicity tests with Daphnia similis were performed to evaluate the toxicity, before and after irradiation.. The data analyzed showed toxicity removal efficiency around 80% for the mixture of Propranolol, Fluoxetine and Diclofenac; 75% for the mixture of Propranolol, Fluoxetine and Sulfadiazine; and 30% for the mixture of Acetylsalicylic acid, Fluoxetine and Metformin. According to the literature, this is a viable technology for the removal of toxicity from pharmaceuticals, and the results demonstrated the potential of electron beam irradiation in reducing the toxicity of pharmaceutical from different classes.

    Palavras-Chave: aquatic ecosystems; contamination; drugs; electron beams; environmental impacts; pollutants; radiation dose units; toxicity; waste water

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✔ O RD disponibiliza um quadro estatístico de produtividade, onde é possível visualizar o número dos trabalhos agrupados por tipo de coleção, a medida que estão sendo depositados no RD.

✔ Na página inicial nas referências são sinalizados todos os autores IPEN, ao clicar nesse símbolo será aberta uma nova página correspondente à aquele autor – trata-se da página do pesquisador.

✔ Na página do pesquisador, é possível verificar, as variações do nome, a relação de todos os trabalhos com texto completo bem como um quadro resumo numérico; há links para o Currículo Lattes e o Google Acadêmico ( quando esse for informado).

ATENÇÃO!

ESTE TEXTO "AJUDA" ESTÁ SUJEITO A ATUALIZAÇÕES CONSTANTES, A MEDIDA QUE NOVAS FUNCIONALIDADES E RECURSOS DE BUSCA FOREM SENDO DESENVOLVIDOS PELAS EQUIPES DA BIBLIOTECA E DA INFORMÁTICA.

O gerenciamento do Repositório está a cargo da Biblioteca do IPEN. Constam neste RI, até o presente momento 20.950 itens que tanto podem ser artigos de periódicos ou de eventos nacionais e internacionais, dissertações e teses, livros, capítulo de livros e relatórios técnicos. Para participar do RI-IPEN é necessário que pelo menos um dos autores tenha vínculo acadêmico ou funcional com o Instituto. Nesta primeira etapa de funcionamento do RI, a coleta das publicações é realizada periodicamente pela equipe da Biblioteca do IPEN, extraindo os dados das bases internacionais tais como a Web of Science, Scopus, INIS, SciElo além de verificar o Currículo Lattes. O RI-IPEN apresenta também um aspecto inovador no seu funcionamento. Por meio de metadados específicos ele está vinculado ao sistema de gerenciamento das atividades do Plano Diretor anual do IPEN (SIGEPI). Com o objetivo de fornecer dados numéricos para a elaboração dos indicadores da Produção Cientifica Institucional, disponibiliza uma tabela estatística registrando em tempo real a inserção de novos itens. Foi criado um metadado que contém um número único para cada integrante da comunidade científica do IPEN. Esse metadado se transformou em um filtro que ao ser acionado apresenta todos os trabalhos de um determinado autor independente das variáveis na forma de citação do seu nome.

A elaboração do projeto do RI do IPEN foi iniciado em novembro de 2013, colocado em operação interna em julho de 2014 e disponibilizado na Internet em junho de 2015. Utiliza o software livre Dspace, desenvolvido pelo Massachusetts Institute of Technology (MIT). Para descrição dos metadados adota o padrão Dublin Core. É compatível com o Protocolo de Arquivos Abertos (OAI) permitindo interoperabilidade com repositórios de âmbito nacional e internacional.

1. Portaria IPEN-CNEN/SP nº 387, que estabeleceu os princípios que nortearam a criação do RDI, clique aqui.


2. A experiência do Instituto de Pesquisas Energéticas e Nucleares (IPEN-CNEN/SP) na criação de um Repositório Digital Institucional – RDI, clique aqui.

O Repositório Digital do IPEN é um equipamento institucional de acesso aberto, criado com o objetivo de reunir, preservar, disponibilizar e conferir maior visibilidade à Produção Científica publicada pelo Instituto, desde sua criação em 1956.

Operando, inicialmente como uma base de dados referencial o Repositório foi disponibilizado na atual plataforma, em junho de 2015. No Repositório está disponível o acesso ao conteúdo digital de artigos de periódicos, eventos, nacionais e internacionais, livros, capítulos, dissertações, teses e relatórios técnicos.

A elaboração do projeto do RI do IPEN foi iniciado em novembro de 2013, colocado em operação interna em julho de 2014 e disponibilizado na Internet em junho de 2015. Utiliza o software livre Dspace, desenvolvido pelo Massachusetts Institute of Technology (MIT). Para descrição dos metadados adota o padrão Dublin Core. É compatível com o Protocolo de Arquivos Abertos (OAI) permitindo interoperabilidade com repositórios de âmbito nacional e internacional.

O gerenciamento do Repositório está a cargo da Biblioteca do IPEN. Constam neste RI, até o presente momento 20.950 itens que tanto podem ser artigos de periódicos ou de eventos nacionais e internacionais, dissertações e teses, livros, capítulo de livros e relatórios técnicos. Para participar do RI-IPEN é necessário que pelo menos um dos autores tenha vínculo acadêmico ou funcional com o Instituto. Nesta primeira etapa de funcionamento do RI, a coleta das publicações é realizada periodicamente pela equipe da Biblioteca do IPEN, extraindo os dados das bases internacionais tais como a Web of Science, Scopus, INIS, SciElo além de verificar o Currículo Lattes. O RI-IPEN apresenta também um aspecto inovador no seu funcionamento. Por meio de metadados específicos ele está vinculado ao sistema de gerenciamento das atividades do Plano Diretor anual do IPEN (SIGEPI). Com o objetivo de fornecer dados numéricos para a elaboração dos indicadores da Produção Cientifica Institucional, disponibiliza uma tabela estatística registrando em tempo real a inserção de novos itens. Foi criado um metadado que contém um número único para cada integrante da comunidade científica do IPEN. Esse metadado se transformou em um filtro que ao ser acionado apresenta todos os trabalhos de um determinado autor independente das variáveis na forma de citação do seu nome.