INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES
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Navegação Eventos - Resumos por Agências de fomento "Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)"

Navegação Eventos - Resumos por Agências de fomento "Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)"

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  • IPEN-DOC 28093

    YOSHIDA, A.C. ; LOPES, F.J.S. ; CACHEFFO, A. ; MOREIRA, G.A. ; SILVA, J.J. da ; LANDULFO, E. . AEOLUS calibration and validation activities at SPU Lidar Station - Brazil. In: EUROPEAN LIDAR CONFERENCE, November 18-20, 2020, Granada, Spain. Resumo expandido... 2020. p. 1-2.

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  • IPEN-DOC 29590

    RAMOS, LUIZ D.; MANTOVANI, MARIANA C. ; SARTORI, ADRIANO; DUTRA, FERNANDO; STEVANI, CASSIUS V.; BECHARA, ETELVINO J.H. Aerobic co-oxidation of hemoglobin and aminoacetone. In: SILVA, FERNANDO de C. da (Org.) REUNIAO ANUAL DA SBQ, 45., 31 de maio - 3 de junho, 2022, Maceió, AL. Resumo... São Carlos, SP: Aptor Software, 2022. p. 164-164.

    Abstract: Aminoacetone (1-aminopropan-2-one), a putative minor biological source of methylglyoxal, reacts like other 􀄮-aminoketones such as 6-aminolevulinic acid (first heme precursor) yielding electrophilic 􀄮-oxoaldehydes, ammonium ion and reactive oxygen species by metal- and hemeprotein catalyzed aerobic oxidation 1,2. A wealth of reports implicates methylglyoxal in protein crosslinking and DNA addition, leading to age-related disorders, including diabetes 3,4. Importantly, methylglyoxal-treated hemoglobin adds four water-exposed arginine residues, which may compromise its physiological role and potentially serve as biomarkers for diabetes 5. In this work, we investigate the co-oxidation of aminoacetone and oxyhemoglobin in normally aerated phosphate buffer, leading to structural changes in hemoglobin, which might reportedly be attributed to the addition of aminoacetone-generated methylglyoxal to the protein. Hydroxyl radical-promoted chemical damage to hemoglobin may also occur in parallel, which is suggested by EPR-spin trapping studies with 5,5-dimethyl-1-pyrroline-N-oxide and ethanol. Concomitantly, oxyhemoglobin is oxidized to methemoglobin, as indicated by characteristic CD spectral changes in the absorption Soret and visible regions. Overall, these findings may contribute to elucidate the molecular mechanisms underlying human diseases associated with hemoglobin dysfunctions (e.g., diabetes) and with aminoacetone in metabolic alterations related to excess of glycine and threonine (e.g., threoninemia, cri-du-chat syndrome).

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  • IPEN-DOC 27448

    BASSO, LUANA; GATTI, LUCIANA ; MARANI, LUCIANO; CASSOL, HENRIQUE; TEJADA, GRACIELA; DOMINGUES, LUCAS ; CORREIA, CAIO ; CRISPIM, STEPHANE; NEVES, RAIANE; IPIA, ALBER; ARAI, EGIDIO; ARAGAO, LUIZ; MILLER, JOHN; GLOOR, MANUEL. Amazon CH4 budget and its controls based on atmospheric data from vertical profiles measurements. In: EGU General Assembly, May 4-8, 2020, Online. Abstract... Göttingen, Germany: Copernicus, 2020.

    Abstract: Wetland emissions are considered the main natural global Methane (CH4) source, but it is budget remains highly uncertain. Tropical regions like the Amazon, host some of the largest wetlands/seasonally flooded areas on the globe. However, tropical regions are still poorly observed with large-scale integrating observations. Here we present the first atmospheric sampling of the lower troposphere over the Amazon using regular vertical profile greenhouse gas and carbon monoxide (CO) observations at four sites. Since 2010 we collected bimonthly CH4, to provide solid seasonal and annual CH4 budgets with large spatial resolution. Vertical profiles are sampled using light aircraft, high-precision greenhouse gas and CO analysis of flask air, fortnightly between 2010 to 2018. The results show a regional variation in CH4 emissions. There are comparably high emissions from the northeast part of the Amazon exhibiting strong variability, with particularly high CH4 fluxes in the beginning of the wet season (January to March). A second period of high emissions occurs during the dry season. The cause of the high emissions is unclear. In the other three sites located further downwind along the main air-stream are observed lower emissions, that represents approximately 25-30% of what is observed in the northeast region and with a clear annual seasonality. In addition, these data show an interannual variability in emissions magnitude, so we discuss how these data can be correlate to climate variables (like temperature and precipitation) and with human-driven changes (like biomass burning) that could be influencing this variability. Over the full period the Amazon (total area of around 7.2 million km2) was a source of CH4, of approximately 46 ± 6 Tg/year, which represent 8% of the global CH4 flux to the atmosphere. Using a CO/CH4 emission ratio calculated in this study we find a biomass burning contribution varying between 10 and 23% of the total flux at each site.

    Palavras-Chave: methane; atmospheres; carbon monoxide; greenhouse gases; wetlands

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  • IPEN-DOC 27994

    CASTRO, PEDRO ; LIMA, CASSIO ; ZORN, TELMA; ZEZELL, DENISE M. . Assessment of burn wounds status using mid-infrared spectroscopy. In: SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE, October 7-9, 2019, São Paulo, SP. Abstract... Piscataway, NJ, USA: IEEE, 2019. p. 20-21.

    Abstract: Burns are one of the major causes of morbidity and the most costly traumatic injuries worldwide. Better understanding of the molecular mechanisms associated with wound healing might provide improved clinical strategies to speed up the tissue repair process and reduce the global impact of burns on public health services. The traditional techniques used to assess the biochemical events related to wound repair are laborious, time-consuming and require multiple staining. Thus, the present study aims to evaluate the feasibility of Fourier transform infrared (FTIR) spectroscopy in order to monitor the progress and healing status of burn wounds. Third-degree burn injuries were induced on Wistar rats by water vapor exposure. Afterwards, biopsies specimen was extracted for further histopathological examination and spectroscopic evaluation at 4 time-points (3, 7, 14 and 21 days). Raw spectral data were offset-corrected and normalized by amide I band area. The second derivatives were compared by the Principal Component Analysis (PCA). On days 3 and 7, when compared to healthy group, biomolecules bands were most prominent. However, on days 14 and 21, these molecular bands decreased. Therefore, our pairwise comparison revealed that metabolic activity induced by thermal injury decreases as the healing process progresses. Our findings show that FTIR spectroscopy can monitor the biochemical development induced by burn injury and detect the status of wound repair.

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  • IPEN-DOC 25613

    CASTRO, PEDRO A.A. de ; ZEZELL, DENISE M. ; MORAIS, MYCHEL R.P.T.; ZORN, TELMA M.T.. ATR-FTIR spectral monitoring of burn wound healing in skin by hierarchical cluster. In: ENCONTRO DE OUTONO, 41., 06-11 de maio, 2018, Foz do Iguaçu, PR. Resumo... São Paulo: Sociedade Brasileira de Física, 2018. p. 1-1.

    Abstract: Efficient biochemical characterization of burn wound healing stages can improve clinical routine to adjust the patient treatment. The Fourier Transform Infrared spectroscopy coupled with Attenuated Total Reflectance (ATR-FTIR) is an analytical technique that has potential capability to provide spectral biomarkers in biological material. This study aims to evaluate the feasibility of using ATR-FTIR to classify burned skin, to be able, in the future, to follow the regenerative process in patients. Wistar rat burn tissues were evaluated by ATRFTIR spectroscopy at 3, 7, 14, 21 days after burn and compared with the healthy group samples (H). For the acquisition of one spectrum, 150 scans were averaged with a resolution of 4 cm-1 and wavenumbers ranging from 4000 to 400 cm-1. Analysis of the spectra was performed using MatLab R2017a (MathWorks, EUA) software. The fingerprint region between 900 to 1800 cm-1 was separated and normalized by amide I band area. For smoothing purpose, spectra were submitted to Savitzky-Golay filter with a polynomial of second order in a fifteen points window. All spectra data were submitted to the hierarchical cluster using the single method and standardized Euclidean distance. The classification results demonstrated separation to non-wounded groups with an accuracy of 91,8% (H vs. 3D), 87,83% (H vs. 7D) and 97,96% (H vs. 14D). Interestingly, when the results from the healthy group were compared to the 21D group, the accuracy dissimilarity was 26%, which suggests that they are chemically similar implying that after 21 days the burned lesions are entirely recovered. These findings indicate that when an adequate multivariate method is applied, ATR-FTIR is suitable to detect the wounded and non-wounded skin as well as its healing stages. In this way, it is possible to conclude that ATR-FTIR can be an auxiliary analysis for the clinical routine for skin burn wound healing.

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  • IPEN-DOC 27072

    AMARAL, M.M. ; TEIXEIRA, L.R.C. ; CARVALHO, M.T.; GOMES, A.S.L.; ZEZELL, D.M. . Avaliação da espessura da epiderme em hemangioma por optical coherence tomography. In: VIEIRA NETO, HUGO (Ed.); SOARES, ALCIMAR B. (Ed.); FÉLIX, RODRIGO P.B. da C. (Ed.); VIEIRA NETO, HUGO (Org.); MAIA, JOAQUIM M. (Org.); PICHORIM, SÉRGIO F. (Org.); GAMBA, HUMBERTO R. (Org.); COSTA, EDUARDO T. (Org.) CONGRESSO BRASILEIRO DE ENGENHARIA BIOMÉDICA, 25., 17-20 de outubro, 2016, Foz do Iguaçu, PR. Resumo... Rio de Janeiro, RJ: Sociedade Brasileira de Engenharia Biomédica, 2016. p. 2331-2331.

    Abstract: Introdução: Os Hemangiomas são lesões vasculares que comumente encontradas na região da cabeça e pescoço, atingindo cerca de 10% das crianças ao redor do mundo [1]. O diagnóstico precoce pode levar ao tratamento das lesões e redução de suas consequências estéticas e psicológicas causadas ao paciente. A biopsia excisional é o padrão ouro para diagnostico a nível celular, porém é uma técnica invasiva e que pode causar efeitos colaterais. As alternativas não invasivas disponíveis são a tomografia computadorizada (CT), a imagem por ressonância magnética (MRI) e o ecografia por ultrassom (US) [1, 2]. Tanto o CT quanto o MRI apresentam um custo proibitivo para aplicações clínicas de rotina. Já o US está presente em hospitais e possui custo mais acessível com aplicações no diagnóstico vascular. A imagens US atinge camadas profundas com resolução e alguns milímetros no do tecido biológico, não atendendo aos hemangiomas que aparecem nas camadas mais superficiais da pele. Uma possível alternativa é a técnica Optical Coherence Tomography (OCT) que produz imagens em seção transversal com resolução micrométrica do tecido biológico utilizando luz. Ela encontra aplicações na dermatologia [3] e pode ser usado para caracterização funcional, óptica ou morfológica de tecido biológico. O objetivo deste trabalho foi avaliar as diferenças de espessura da epiderme em regiões de lesão vascularizada e normal utilizando a técnica OCT. Materiais e Métodos: As imagens OCT foram adquiridas utilizando-se um sistema OCT swept source com resolução axial de 9 μm e lateral de 18 μm. As imagens possuem 512x1024 pixel (axial x lateral) e foram adquiridas a uma taxa de 25 quadros / s. Este estudo foi aprovado pelo Comitê de Ética do IMIP (protocolo no. 728.993). Neste estudo fo ram utilizadas imagens da mão de um paciente nas regiões de hemangioma e pele sadia, possibilitando a identificação de suas diferenças. Foi implementado um algoritmo em ambiente Matlab para determinar a espessura da epiderme em todas as 541 imagens de lesão vascularizada e as 50 de pele normal. Resultados: Através da medição automatizada da espessura da epiderme na região de lesão e sadia (figura 1) foi possível observar a distribuição de profundidade em cada uma destas regiões. A região de lesão possui uma distribuição de profundidade mais estreita e com espessura menor que a de pele normal. Já a região de pele normal apresenta uma distribuição mais larga, porém com dois valores de maior probabilidade, isso se deve tanto a presença de glândulas mais visíveis na pele sadia quanto a uma maior presença de papilas dérmicas na junção derme-epiderme. Conclusões: A medição da espessura da epiderme mostrou-se válida como um possível marcador da presença de hemangioma. O uso desta abordagem poderia ser complementar a outros marcadores possíveis de serem extraídos do sinal OCT. A ampliação do painel de estudo e comparação com outras técnicas padrão ouro deverá ser realizada em futuros estudos.

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  • IPEN-DOC 24937

    CASTRO, PEDRO A.A. de ; DIAS, DERLY A. ; VELOSO, MARCELO N. ; ZEZELL, DENISE M. . Biochemical evaluation of bone submitted to ionizing radiation by ATR-FTIR spectroscopy. In: CONFERENCE ON LASERS AND ELECTRO-OPTICS, May 14-19, 2017, San Jose, California, USA. Resumo expandido... Washington, DC, USA: OSA, 2017.

    Abstract: FTIR spectroscopy associated with PC-LDA was able to discriminate bone samples receiving different ionizing radiation doses (0,01 kGy, 1 kGy, 15 kGy), showing potential to the use of phosphate vibrational modes as a dose marker. OCIS codes: (170.4580) Medical optics and biotechnology – Optical diagnostics for medicine; (170.6510) Medical optics and biotechnology – Spectroscopy, tissue diagnostics; (170.1580) Medical optics and biotechnology – Chemometrics.

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  • IPEN-DOC 28122

    DEL-VALLE, M. ; SANTOS, M.O. ; SANTOS, S.N. dos ; BERNARDES, E.S. ; ZEZELL, D.M. . Breast cancer estrogen and progesterone receptors evaluation using FTlR spectroscopy imaging: a pilot study. In: IUPAB CONGRESS; ANNUAL SBBF MEETING; ANNUAL SBBQ MEETING, October 26-30, 2020, Foz do Iguaçu, PR. Abstract... 2020.

    Abstract: INTRODUCTION. Breast cancer is the second leading cause of cancer death in woman worldwide with an incidence of 2.09 million and 627 thousand deaths in 2018. Histopathology is the gold standard method for cancer diagnosis and identification of therapeutic targets, however it still presents interpretation difficulties, especially when comparing different cancer subtypes. OBJETICVE: The aim of this study was to evaluate Fourier transform infrared (FTIR) spectroscopy in the diagnose and differentiation of molecular differences between two different breast cancer subtypes: positive and negative for estrogen (ER) and progesterone (PR) receptors. METHODS: Two human breast cell lines, BT474 (ER and PR positive) and SKBR3 (ER and PR negative), were inoculated in Balb/c nude mice. Tumors were collected when reached 0.5 cm3, processed by formalin fixation and paraffin embedding. 5μm thick tissue cuts were fixed in low-e slides (MirrIR, Kevley Technologies). Spectral images were performed in a micro-FTIR (Cary 660, Agilent Technologies) with 32 x 32 FPA of 5.5 μm pixel size. Scattering correction (RMieS-EMSC) was performed using MATLAB and remaining processing using Python. Groups differentiation were evaluated by PCA from 1350 to 1000 cm-1 second derivatives. RESULTS AND DISCUSSION: Groups were split in two clusters, separated by PC-1 with a 99 % accuracy in both groups and 45 % of explained variance. The absorptions in the selected region for the PCA were mainly related to DNA, RNA and protein content. The main contribution was presented by the 1238 cm-1 peak, which was correlated with nucleic acids symmetrical stretching. Hyperspectral image built from this peak presented a spatial correlation with the microscope white light imaging, indicating that possible region for histopathological correlation might be present. CONCLUSAO: Our pilot study shows that FTIR spectroscopy imaging can distinguish ER/PR positive from negative breast cancer subtypes.

    Palavras-Chave: neoplasms; mammary glands; diagnostic techniques; histology; fourier transformation; infrared spectra

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  • IPEN-DOC 26005

    ZAMATARO, CLAUDIA B. ; KUCHAR, NIELSEN G. ; SCAPIN, MARCOS A. ; ZANINI, NATHALIA ; CASTRO, PEDRO ; RABELO, THAIS F. ; JUVINO, AMANDA C. ; ZEZELL, DENISE . Calcium analysis from gamma sterilized human dentin and enamel. In: ENCONTRO DE OUTONO DA SOCIEDADE BRASILEIRA DE FÍSICA, 42., 26-31 de maio, 2019, Aracaju, SE. Resumo... São Paulo: Sociedade Brasileira de Física, 2019.

    Abstract: Gamma radiation changes the patients0 oral cavity undergoing radiotherapy. Alterations cause an unsaturated environment of calcium and phosphate into the oral cavity. After approval of the Ethics Committee, 20 hu- man teeth were sectioned to obtain 20 human enamel and 20 dentin samples, polished plane. Samples were randomized in the irradiated group and control group (untreated). Then, the treatment group was irradiated with 25:0 kGy at the 60Co multipurpose irradiator. After the gamma irradiation, Fourier Transformed Infrared Spectroscopy (FTIR), percentage of surface microhardness loss (%SMHL) and Scanning Electron Microscopy (SEM) were performed. At the end, acidic biopsies were performed to quantify the concentration of calcium present in the samples. FTIR showed that the molecular structure of HA of the enamel is similar to the non- irradiated, with no formation or loss of molecular compounds occurring. X-ray °uorescence at enamel samples was performed. Microscopic morphological analysis did not shown signi¯cant di®erences. Surface microhardness is an indirect indicator of the mineral content of the samples. The mean obtained was 258:2 (38:8) KHN within the hardness spectrum of the healthy natural enamel. The compounds present in the samples and the values of the ratios of Calcium and Phosphate oxides and relation between the elements Calcium and Phosphorus. The ratio of the most stable oxides shows a variation with linear correlation. In the enamel, the ratio (Ca/P) shows a change in the elemental content with linear correlation (R2 = 1). These ¯ndings lead us to a new hypothesis of behaviour of the HA crystal versus gamma irradiation. On the other hand for the irradiated dentin, the Knoop hardness number was within the range of the spectrum similar to that of natural dentin of human origin. X-ray °uorescence shows that irradiated dentin has great similarity with natural dentin from the point of view of chemical composition. SEM analyses showed that there was no thermal damage or interprismatic morpho- logical changes in the hydroxyapatite structure of human dental dentin outside the buccal environment when using doses of gamma irradiation up to 25 kGy.

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  • IPEN-DOC 26015

    GONZALES-LORENZO, CARLOS; WATANABE, SHIGUEO; BUENO, CARMEN ; KODAIRA, SATOSHI; NASCIMENTO, LUANA. CaSiO3 polycrystal for neutron, proton and carbon detection. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 20-20.

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  • IPEN-DOC 29563

    TAPPIZ, BRUNO ; SILVA, PAULO S.C. da ; OSTERMANN, CAROLINE ; LIMA, NICOLE P. de ; ANDRADE, MARIANA N. de ; BUSTILLOS, OSCAR V. . Comparison of 238U mass fraction measured by ICP–MS and Instrumental Neutron Activation Analysis techniques. In: SIMIONATO, ANA V.C. (Coord.) IBEROAMERICAN CONFERENCE ON MASS SPECTROMETRY, 3rd, December 10-15, 2022, Rio de Janeiro, RJ. Abstract... Campinas, SP: Sociedade Brasileira de Espectrometria de Massas - BrMASS, 2022. p. 237-238.

    Abstract: Introduction: Uranium is an element present in ambient air, water, soil and rocks [1]. The most abundant natural radioisotope of this actinide (238U) produces in its chain decay the radionuclide 222Rn [2], which is a tracer for atmospheric mixing and transport model validations [3]. The 238U activity concentration in superficial soil samples is a crucial parameter for some 222Rn flux map modeling methodologies [4]. Methods: In this study, 18 superficial soil samples were analyzed. The content of 238U was assessed using two techniques: (i) by the comparative method of the Instrumental Neutron Activation Analysis (INAA) [5] and by ICP–MS (ELAN 6000, PerkinElmer) [6]. Certified Reference Materials (CRM) SRM 1646a Estuarine Sediment and USG STM–2 were used both as comparators in the INAA technique and to ensure quality control. The normality and homoscedasticity of the data were evaluated. Finally, the Mann- Whitney U test [7] was used to assess whether or not there is a significant difference (α = 0.05) between the two techniques. Results: The z-score was calculated to ensure quality control. Z-scores values was obtained by the Modified Horwitz Equation [8], which takes into account the order of magnitude of the content of the analyte and is independent of the CRM uncertainties, unavailable for the CRM used. The z-score values obtained (n = 3) for the radionuclide 238U were 0.5 for the CRM USG STM–2 and -0.4 for SRM 1646a. The z-scores obtained are smaller than 2 therefore they are considered satisfactory [9]. Regarding the statistical parameters of the comparison between the techniques, the normality (Shapiro Wilk) was not verified (p = 0.02 for ICP-MS and p = 0.03 for INAA). The p-value for the test for equal variances (F test) was 0.71 Mann-Whitney U test was used instead of Student’s test due to the non-verification of the normality parameter in the data. The p-value from the Mann-Whitney test (0.51) indicates that there is no significant difference between the 238U content measured by the two techniques. Conclusions: Statistical analysis showed that there is no significant difference between the 238U mass fraction measured by the ICP–MS and the INAA – comparative method. In the future, certified reference materials will also be assessed by ICP–MS in order to corroborate this statistical comparison from a metrological point of view.

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  • IPEN-DOC 26023

    SOARES, MARIA R. ; SANTOS, WILLIAM S.; NEVES, LUCIO P.; PERINI, ANA P. ; MAIA, ANA; BELINATO, WALMIR; CALDAS, LINDA V.E. . Computational modeling of thyroid shields and lead eyewear and the impact on the absorbed doses of eye lens and thyroid gland in CBCT exams. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 56-56.

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  • IPEN-DOC 26029

    LIMA, CAIO L.; AMARAL, CAIO E.S.; BELINATO, WALMIR; NEVES, LUCIO P.; PERINI, ANA P. ; SANTOS, WILLIAM S.; ALMEIDA, EDSON P.B. de; NAVARRO, MARCUS V.T.. Computational simulation of the detectors designed for computer tomography. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 102-102.

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  • IPEN-DOC 26826

    GIAROLA, JOSEANE M.; PEREIRA, GUALTER S.; KUGELMEIER, CRISTIE L.; TERADA, MAYSA ; MARCOMINI, JOSE B.; ROVERE, CARLOS A.D.; AVILA, JULIAN A.; BOSE FILHO, WALDEK W.. Corrosion behavior of friction stir welded API X70 steel joints. In: BRAZIL MRS MEETING, 18th, September 22-26, 2019, Balneário Camburiú, SC. Abstract... São Carlos, SP: Aptor Software, 2019. p. 2171-2171.

    Abstract: The ever-increasing demand for fossil fuels has pushed the oil and gas industry to search for new deep water wells and in more aggressive environmental conditions, such as the pre salt where the presence of CO2 and H2S concentrations, has led to the development of new materials and manufacturing processes. For pipeline construction, Friction Stir Welding (FSW) process is a promising candidate to be used in the girth welding procedure, and research studies must be carried out to understand the effect of this new processing on the pipeline life under the in-service conditions (environment, fatigue). The present work is part of a research project aiming to investigate the effect of a saline environment on the mechanical properties of an API-5L-X70 steel, welded by FSW. Therefore, in this work, the results of the corrosion behavior analysis carried out on the FSW welded joint, considering a 3.5% NaCl solution, are presented. The corrosion behavior was investigated based on potentiodynamic polarization tests on the different regions of FSW welded joint, i.e., the base metal (BM) and stirred zone (SZ). Gel visualization tests, considering the whole welded joint, were also conducted. The two FSW regions showed similar polarization curves in terms of corrosion potential (Ecorr), corrosion current density (icorr) as well as anodic current density values. In the gel tests, a preferential localized attack on any of the regions of the FSW welded joint was not observed. These results can be interpreted as evidence that the corrosion behavior of the FSW welded joint was not significantly affected by the different metallurgical microstructures formed by the FSW processing.

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  • IPEN-DOC 24503

    COURROL, LILIA C.; SAMAD, RICARDO E. . Determination of chicken meat contamination by porphyrin fluorescence. In: INTERNATIONAL CONFERENCE ON LUMINESCENCE, 18th, August 27 - September 01, 2017, João Pessoa, PB. Abstract... 2017. p. 220-220.

    Abstract: Meat quality is normally defined by the combination of factors such as visual appearance, smell, firmness, succulence, tenderness, and flavor[1-3]. Contamination of poultry meat with pathogens remains an important public health issue, because it can lead to illness due to negligence in handling, cooking or post-cooking storage of the product. Conventionally, quality tests of meat are assessed by visual evaluation or chemical analysis, which has the disadvantages of being subjective and time-consuming. To improve the detection accuracy and production efficiency, it is proposed the evaluation of porphyrin [4] contents of meat by fluorescence spectroscopy, considering that most microorganisms and animal cells excrete porphyrins. For this purpose, chicken meat was cut in small pieces, and separated in three groups; the control group where the meat was conserved under refrigeration and experimental groups where the meat pieces were kept for 24 and 30 hs at room temperature. Porphyrin was extracted from the meat and the fluorescence was measured in the range 550–750 nm, exciting samples around 400 nm. Fluorescence lifetime was also studied. To ensure porphyrin synthesis, a concentration of 9.3 mM of δ-Aminolevulinic acid (ALA) was added to meat 2 hs before porphyrin extraction. The results have shown that the porphyrin fluorescence increased in meat kept at room temperature and incubated with ALA, due to the presence of microorganisms, indicating a new method to test meat quality.

    Palavras-Chave: animal cells; chemical analysis; animals; chickens; contamination; meat; fluorescence spectroscopy; porphyrins; food; emission spectroscopy; organic compounds

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  • IPEN-DOC 25025

    HERRERA, CRISTHIANO C. ; SAMAD, RICARDO E. ; VIEIRA JUNIOR, NILSON D. ; ROSSI, WAGNER de . Development and control of microfluidic systems. In: WORKSHOP INFO, 1., 01 de julho, 2017, Recife, PE. Resumo expandido... 2017.

    Abstract: The first stage of the project was to perform tests for controlled and optimized machining of BK7 optical glass by femtosecond laser. Parameters such as energy, overlapping pulses, and the focal position variation were investigated for a better extraction of the material. Microchannels, microvalves, micropumps, mixers, reactors, heaters and other components were developed to compose applied microfluidic systems. Microchannels built in BK7 glass separated by a PDMS film form the basis of the microfluidic circuits. The reagent flow control is done by pneumatic mini-valves controlled by an Arduino microcontroller through a Labview platform. This work shows the components developed and two microfluidic systems created. The first contains a microfluidic circuit capable of replicating enzyme-linked immunosorbent assays (ELISA) with a much lower cost of materials. The second has a microfluidic circuit for the production of NaYF4 fluorescent nanocrystals specially used as markers in images of biological systems.

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  • IPEN-DOC 25512

    GOMES, A.A. ; BUSTILLOS, J.O.W.V. ; VIANNA JUNIOR, A.S.; LANDULFO, E. ; ROSSI, W. de . Development of a microfluidic circuit "microreactor" to atmospheric analyses. In: WORKSHOP LIDAR MEASUREMENTS IN LATIN AMERICA, 10th, November 19-23, 2018, Medellín, Colombia. Abstract... 2018.

    Palavras-Chave: air pollution; atmospheric chemistry; troposphere; ozone; temperature control; measuring instruments; microstructure

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  • IPEN-DOC 29201

    TEODORO, LARA E.H. ; TALACIMON, CRISTHIAN F. ; ROSERO, WILMMER A.A. ; RIGO, MARIA E.Z. ; RODRIGUES, PRISCILA S. ; NOGUEIRA, THUANY C. ; ANGELOCCI, LUCAS V. ; ROSTELATO, MARIA E.C.M. . Development of a new material to encapsulate phosphorus-32 for use in brachytherapy. In: BRAZIL MRS MEETING, 20th, September 25-29, 2022, Foz do Iguaçu, PR. Abstract... São Carlos, SP: Aptor Software, 2022.

    Abstract: The term cancer refers to a set of malignant diseases that have in common the disordered growth of mutated cells, which can invade adjacent tissues or distant organs[1]. In 2020, cancer of the central nervous system (CNS) represented 1.6% of all new malignant tumor cases in the world, and about 2.5% of all new cancer deaths[2]. A promising radioactive source for use in intracavitary brachytherapy is phosphorus-32. This source has been prominent as a minimally invasive treatment for craniopharyngiomas and in the treatment of metastatic bone diseases in general[3]. To encapsulate phosphorus-32 and make it a viable radioactive source for use in medicine, some methods have emerged. In this work, we are developing a fabric soaked in industrial latex for this purpose, as this source comes in the form of orthophosphoric acid in aqueous solution and as industrial latex is soluble in water. Tests carried out so far show that the material supports orthophosphoric acid while is still malleable, which is essential for treating spinal cancer.

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  • IPEN-DOC 26797

    GUIMARÃES, V.P.; NANDENHA, J. ; FATIBELLO-FILHO, O.; NETO, A.O. ; VICENTINI, F.C.; ASSUMPÇÃO, M.H.M.T.. Development of nanomaterials for formate electrochemical oxidation aiming sustainable energy generation. In: ANDRADE, ADALGISA R. de (Ed.); ALMEIDA, ERICA J.R. de (Ed.); OLIVI, PAULO (Ed.) SIMPÓSIO BRASILEIRO DE ELETROQUÍMICA E ELETROANALÍTICA, 22nd, 1-5 de setembro, 2019, Ribeirão Preto, SP. Resumo... Ribeirão Preto, SP: Sociedade Brasileira de Eletroquímica e Eletroanalítica, 2019. p. 436-436.

    Abstract: The world energy system is highly depended of fossil fuels, which is not sustainable [1]. Thus, the use of alternative energy is crucial and fuel cells are being considered good options. In this context, this work aimed to develop electrocatalysts based on palladium nanoparticles (PdNPs) supported on the physical mixtures of carbon (Vulcan XC72) and titanium dioxide (P25) toward formate oxidation in alkaline medium and its application in formate fuel cells. The materials were synthesized by the borohydride reduction method [2] with 20% (m/m) of metal loading and in two batches. In the first batch, the PdNPs were reduced in the physical mixture of carbon (C) and titanium dioxide (TiO2), in different proportions of C and TiO2, identified as Pd/(C+TiO2), while in the second one, the PdNPs were reduced only in TiO2 with later incorporation of C which were identifies as Pd/TiO2-C. On both batches, the ratios between C and TiO2 used were 75:25, 50:50 and 25:75 (m/m). A reference material, complied of PdNPs supported just on C (Pd/C) was also prepared. All materials were characterized by X-ray diffraction, showing peaks of the face-centered-cubic (fcc) structure of the Pd, as well as TiO2 peaks of anatase and rutile phases. Transmission Electron Microscopy (TEM) were also evaluated showing an average particle size between 3 and 8 nm. Electrochemical experiments considering voltammetry and chronoamperometry showed that the materials with PdNPs reduced in the TiO2 (Pd/TiO2-C) were more promising when compared to Pd/(C+TiO2), and among them Pd/TiO2-C 75:25 presented the highest current observed in chronoamperometry. Comparing the Pd/(C+TiO2) materials, the Pd/(C+TiO2) 50:50 presented the highest current. Taking into account single cell experiments, although the electrochemical results evidenced the improvement toward formate with PdNPs deposited firstly in the TiO2, the fuel cell tests showed the opposite, presenting the best cell efficiencies with Pd/(C+TiO2) materials, where Pd/(C+TiO2) 75:25 (ratio between C and TiO2) was the best material with the highest power density obtained. This fact can be explained by the higher conductivity of C, in a higher proportion, coupled with the small amounts of TiO2, which provides oxygenated species that facilitate the formate oxidation.

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  • IPEN-DOC 25604

    LIMA, CASSIO A. ; CORREA, LUCIANA; BYRNE, HUGH J.; ZEZELL, DENISE M. . Diagnosis of advanced skin cancer using Infrared spectral histopathology. In: LATIN AMERICA OPTICS AND PHOTONICS CONFERENCE, November 12-15, 2018, Lima, Peru. Resumo expandido... Washington, DC, USA: OSA, 2018.

    Abstract: In this study, we investigated the feasibility of Infrared Spectral Histopathology to diagnose invasive squamous cell carcinoma using hematoxylin and eosin stained tissue placed on conventional glass slides, as used in the pathologist workflow.

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A pesquisa no RD utiliza os recursos de busca da maioria das bases de dados. No entanto algumas dicas podem auxiliar para obter um resultado mais pertinente.

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O gerenciamento do Repositório está a cargo da Biblioteca do IPEN. Constam neste RI, até o presente momento 20.950 itens que tanto podem ser artigos de periódicos ou de eventos nacionais e internacionais, dissertações e teses, livros, capítulo de livros e relatórios técnicos. Para participar do RI-IPEN é necessário que pelo menos um dos autores tenha vínculo acadêmico ou funcional com o Instituto. Nesta primeira etapa de funcionamento do RI, a coleta das publicações é realizada periodicamente pela equipe da Biblioteca do IPEN, extraindo os dados das bases internacionais tais como a Web of Science, Scopus, INIS, SciElo além de verificar o Currículo Lattes. O RI-IPEN apresenta também um aspecto inovador no seu funcionamento. Por meio de metadados específicos ele está vinculado ao sistema de gerenciamento das atividades do Plano Diretor anual do IPEN (SIGEPI). Com o objetivo de fornecer dados numéricos para a elaboração dos indicadores da Produção Cientifica Institucional, disponibiliza uma tabela estatística registrando em tempo real a inserção de novos itens. Foi criado um metadado que contém um número único para cada integrante da comunidade científica do IPEN. Esse metadado se transformou em um filtro que ao ser acionado apresenta todos os trabalhos de um determinado autor independente das variáveis na forma de citação do seu nome.

A elaboração do projeto do RI do IPEN foi iniciado em novembro de 2013, colocado em operação interna em julho de 2014 e disponibilizado na Internet em junho de 2015. Utiliza o software livre Dspace, desenvolvido pelo Massachusetts Institute of Technology (MIT). Para descrição dos metadados adota o padrão Dublin Core. É compatível com o Protocolo de Arquivos Abertos (OAI) permitindo interoperabilidade com repositórios de âmbito nacional e internacional.

1. Portaria IPEN-CNEN/SP nº 387, que estabeleceu os princípios que nortearam a criação do RDI, clique aqui.


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O Repositório Digital do IPEN é um equipamento institucional de acesso aberto, criado com o objetivo de reunir, preservar, disponibilizar e conferir maior visibilidade à Produção Científica publicada pelo Instituto, desde sua criação em 1956.

Operando, inicialmente como uma base de dados referencial o Repositório foi disponibilizado na atual plataforma, em junho de 2015. No Repositório está disponível o acesso ao conteúdo digital de artigos de periódicos, eventos, nacionais e internacionais, livros, capítulos, dissertações, teses e relatórios técnicos.

A elaboração do projeto do RI do IPEN foi iniciado em novembro de 2013, colocado em operação interna em julho de 2014 e disponibilizado na Internet em junho de 2015. Utiliza o software livre Dspace, desenvolvido pelo Massachusetts Institute of Technology (MIT). Para descrição dos metadados adota o padrão Dublin Core. É compatível com o Protocolo de Arquivos Abertos (OAI) permitindo interoperabilidade com repositórios de âmbito nacional e internacional.

O gerenciamento do Repositório está a cargo da Biblioteca do IPEN. Constam neste RI, até o presente momento 20.950 itens que tanto podem ser artigos de periódicos ou de eventos nacionais e internacionais, dissertações e teses, livros, capítulo de livros e relatórios técnicos. Para participar do RI-IPEN é necessário que pelo menos um dos autores tenha vínculo acadêmico ou funcional com o Instituto. Nesta primeira etapa de funcionamento do RI, a coleta das publicações é realizada periodicamente pela equipe da Biblioteca do IPEN, extraindo os dados das bases internacionais tais como a Web of Science, Scopus, INIS, SciElo além de verificar o Currículo Lattes. O RI-IPEN apresenta também um aspecto inovador no seu funcionamento. Por meio de metadados específicos ele está vinculado ao sistema de gerenciamento das atividades do Plano Diretor anual do IPEN (SIGEPI). Com o objetivo de fornecer dados numéricos para a elaboração dos indicadores da Produção Cientifica Institucional, disponibiliza uma tabela estatística registrando em tempo real a inserção de novos itens. Foi criado um metadado que contém um número único para cada integrante da comunidade científica do IPEN. Esse metadado se transformou em um filtro que ao ser acionado apresenta todos os trabalhos de um determinado autor independente das variáveis na forma de citação do seu nome.